I² StatisticClinical

Percentage of between-study variability in a meta-analysis due to true heterogeneity.

I² quantifies what proportion of the variation in effect estimates across pooled studies reflects genuine heterogeneity rather than chance, usually reported alongside a pooled effect size such as SMD. Its absence, as noted in this review, makes it impossible to judge how consistent the underlying study results actually were.

Appears in these appraisals
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This guide was auto-drafted and is pending editorial review.